Tri Widyawati
University of Sumatera Utara, Indonesia
Title: Effect of Lawsonia inermis Linnaeus leaf extracts on blood glucose level in normal and streptozotocininduced diabetic rats
Biography
Biography: Tri Widyawati
Abstract
Lawsonia inermis Linnaeus is one of the plants commonly used in Indonesian community for the treatment of different diseases. The anti-diabetic activity was evaluated by determining whether the extracts lowered the blood glucose level BGL0 of normal rats (hypoglycemic test) or lowered BGL of streptozotocin-induced diabetic rats (SDR). Dried powdered L. inermis leaves were extracted serially with n-hexane (HE), ethylacetate (EAE), ethanol (EE), water1(WE1) and water2 (WE2). Hypoglycemic in normal rats showed only HE significantly reduce fasting BGL at 3 h observation. However, in antihyperglycemic test in SDR, single-dose administration of the extracts showed that only EAE reduced BGL signficantly at 3 h observation. The present work conclude that EAE is the most active extract as antihyperglycemic.