31^st International Conference on Clinical Diabetes, Diabetic Medication & Treatment September 05-06, 2022 Paris, France

Diabetes Conference 2022 gives a phase to meet people in the experimentation field and thusly, it takes delight in opening an anteroom to encounter the limit in the field, young experts, and potential World-popular speakers, the most recent approaches, methodologies, and the present update in the field of diabetes. Current advances in endocrinology and assimilation, diabetes genetic characteristics, clinical diabetes, diabetic challenges, diabetes prescriptions and pharmacotherapy, and cell treatment for diabetes are the standard sessions to be analyzed in this diabetes meeting. Diabetes is one of the rising sicknesses, which is wrapping up extraordinarily major these days. To get creative, the social event will base on the most recent and animating enhancements in each piece of Diabetes get-togethers, we examine offering a remarkable open portal for overall explorers to collect, system, and handle new genuine movements. 

Diabetes Conference 2022  will feature the latest developments in research, diagnosis, and prevention of diabetes, new insulin analogs, and new technologies and devices for diabetes.

The Editors will concentrate on studies that involve wisely selected reports that provide a link between basic research and translation to diabetes-related diseases. The editors support the diffusion of distinctive solutions to challenging scientific and translational questions related to studies of Diabetes and metabolically/genetically related disorders. 

Presumably, scientists in all disciplines related to Diabetes and various scientists devoted to Glucose Metabolic Homeostasis and related subjects will engage as authors of JDRT articles. Most likely those studies would be focused on indicators of disease risk and mechanisms of glucose metabolic dysregulation-related diseases.

List of Diabetes Universities Worldwide

• Monash University Malaysia
• International Medical University
• Asia Pacific University of Technology and Innovation
• Albert Einstein-Mount Sinai Diabetes Center
• Columbia University
• Indiana Diabetes Research Center 
• Joslin Diabetes Center-Harvard Medical School
• Stanford Diabetes Research Center
• The University of Chicago Diabetes Research 
• Washington University at St. Louis
• Kaiser Foundation Research Institute, California San Francisco
• University of Cambridge
• Johns Hopkins University
• Yale University
• University of California, Los Angeles (UCLA)
• Imperial College London
• University of Melbourne
• Karolinska Institute

Diabetic drugs:

The 50+ diabetes drugs are available in the world in the form of tablets or injection suspension and placed into different drug classes.

• Insulin
• Biguanides / Metformin
• Sulphonylureas
• Meglitinides / Prandial glucose regulator / Glinides
• Alpha-glucosidase inhibitors
• Thiazolidinedione / Glitazones
• DPP-4 inhibitors / Gliptins
• Incretin mimetics / GLP-1 analogues
• Amylin analogues

 

Track 01: Diabetes and Endocrinology

Diabetes is a disease that occurs when your blood glucose is too high. Blood glucose is your main source of energy that comes from the food you eat. Insulin, a hormone made by the pancreas, helps glucose from food to get into your cells to be used for energy. Sometimes your body doesn’t make insulin well. Glucose then stays in your blood and doesn’t reach your cells. Endocrinology is the study of medicine that relates to our endocrine system, which is the system that controls hormones. Endocrinologists are specially trained physicians who diagnose diseases related to the glands. Because these doctors specialize in these conditions, which can be complex and have hard-to-spot symptoms, an endocrinologist is your best believer when dealing with hormonal issues. The endocrinologist's goal is to restore hormonal balance in our body.

 

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Track 2: Advanced technologies for the treatment of diabetes:

The artificial pancreas bridges of diabetes technology that already exist: the insulin pump and the continuous glucose monitor (CGM). A large percentage of world population is affected by diabetes mellitus, out of which approximately 5-10% with type 1 diabetes while the remaining 90% with type 2 diabetes. Insulin administration is essential for the patients of type 2.

Present insulin delivery systems are available as transdermal injections. Several approaches for insulin delivery are being pursued by pharmaceutical companies to reduce the pain, and hypoglycaemic incidences associated with injections.

Informatics in the service of medicine; telemedicine, software and other technologies

New insulin delivery systems: Inhaled, transdermal, and implanted devices

Blood glucose monitoring: Glucose pumps and sensors

Insulin pumps and insulin infusion systems

Insulin secretion in vitro and exocytosis

Insulin Pens and novel Insulin delivery techniques

Acupuncture for diabetic complications

Glucose sensors (invasive and non-invasive)

Closed-loop system and algorithm

 

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Track 3: Global Market for Diabetes and its Research:

Diabetic drugs have the highest market shares amongst drugs and devices compared to other and are also expected to have the highest rate in growth with a CAGR of 8.9%. Diabetic drugs are highly priced it would be one of the major drawbacks.

Diabetic devices include insulin delivery devices and blood glucose meters. The market for blood glucose meters is having the top market shares compared to the insulin delivery systems such as syringes and injection pens. Meter and strips are one of the most expected to dominate the overall market share in diabetic devices.

Global Demographics & Market Dynamics

Comprehensive research methodology of Diabetes market

Analysis of regional regulations

Insights about market determinants

Global Challenges and Unmet Needs

Comprehensive research methodology of Diabetes market

 

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Track 04: Cardiovascular risk in Type 2 Diabetes

Cardiovascular disease (CVD) is the leading cause of death among the non-communicable diseases (NCDs). By reducing the prevalence of behavioural (CVD) risk factor like diabetes. According to the National NCD Risk Factors Survey in 2007, the prevalence of diabetes mellitus (DM) was 14.3%, Hypertension (HTN) was 38.2%, and high cholesterol level was 40.6%. Mortality from cardiovascular disease is increased by a factor of two to three in persons with diabetes as compared with the general population.

 

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Track 05: Diabetic Disorders and Treatment

There is variety of conditions related to diabetes. These include coeliac disease, Thyroid disease and haemochromatosis. Treatment for diabetes requires keeping close watch your blood glucose levels (and keeping them at a goal set by your doctor) with a mixture of medicines, exercise, and diet. By paying close attention to what and once you eat, you'll minimize or avoid the "seesaw effect" of rapidly changing blood glucose levels, which may require quick changes in medication dosages, especially insulin.

 

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Track 06: Diabetes and Obesity

Central obesity as well as obesity in general is associated with physiological changes that may cause the development of diseases like high blood pressure, heart disease, high blood cholesterol and type 2 diabetes. Diabetes is defined as the inability of the body to regulate and control the blood sugar levels. Persistent and long term raised blood sugar is associated with damage to blood vessels, nerves and several organs. Obesity is a complex disease that is associated with a number of comorbidities, exaggerated mortality and reduced quality of life. With the rise in obesity among the older adult population, the cost burden is predicted to increase substantially: the combined medical costs associated with treatment of obesity-related diseases, cardiovascular diseases, and diabetes in the US alone have been estimated to increase by $48-66 billion/year from 2010 through 2030 according to Endocrine Facts and Figures.

 

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Track 07: Gestational Diabetes                                       

Hyperglycemia, which is first detected during pregnancy, is also known as gestational diabetes mellitus (GDM). Although it can occur anytime during pregnancy, GDM generally affects pregnant women during the 2nd and 3rd trimesters. According to the American Diabetes Association (ADA), GDM complicates 7% in all pregnancies.

Treatment for gestational diabetes aims to keep blood glucose levels equivalent to those of pregnant women who don't have gestational diabetes. The treatment always includes special meal plans and scheduled physical activity, and it may also include daily blood glucose testing and insulin injections.

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Track 08: Diabetes Ophthalmology

Diabetes Ophthalmology is a diabetic eye disease. Diabetic eye disease is a group of eye problems that can affect people with diabetes. These conditions include diabetic retinopathy, diabetic macular enema, cataracts, and glaucoma. Over time, diabetes can cause damage to your eyes that can lead to very poor vision or even blindness. But you can take steps to prevent diabetic eye disease, or keep it from getting worse, by taking care of your diabetes.

The best ways to manage your diabetes and keep your eyes healthy are to:

• Manage your blood glucose, blood pressure, and cholesterol, sometimes called the diabetes ABCs
• If you smoke, get help to quit smoking
• Have a dilated eye exam once a year

 

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Track 09: Reproductive Endocrinology

Reproductive endocrinology is a medical specialty for infertility, menopause, and other issues with reproductive hormones. Reproductive endocrinologists are obstetrics (OB) and gynecology (GYN) doctors with special training to help both men and women with problems related to reproductive hormones. Sometimes, this specialty is called reproductive endocrinology and infertility because much of their work focuses on helping women to become pregnant and carry a baby to term.

 

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Track 10: Endocrine Glands and Hormones

The endocrine system is made up of the endocrine glands that discharge hormones. Although there are eight major endocrine glands are Pituitary, Thyroid, Adrenal, Testis, Pineal, Thymus, Pancreas, Ovary) scattered throughout the body, they are still considered to be one system because they have similar functions, similar mechanisms of influence, and many important interrelationships.

Some glands also have non-endocrine regions that have functions other than hormone discharge. As like, the pancreas has a major exocrine portion that secretes digestive enzymes and an endocrine portion that secretes hormones. The ovaries and testes secrete hormones and also produce the ova and sperm. Some organs, like stomach, intestines and heart, produce hormones, but their primary function is not hormone secretion.

 

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Track 11: Diabetes and Periodontitis

Diabetes is a condition of the body that uses digested food for growth and energy. There are mainly 3 types of diabetes are there: type 1, type 2, and gestational diabetes. Periodontitis diseases are infections of the gums and bone that hold the teeth in place. Gum disease has a problem that can happen if you have diabetes and that cannot be controlled well. Also, the body's response to gum infections can result into blood sugar problems. Periodontitis is recognized as the sixth major complication of diabetes, having increased prevalence and sternness in patients with diabetes. Early diagnosis of diabetes in patients with periodontitis can lead to the prevention of major disease and mortality associated with the disease. Therapy for diabetes may also lead to the improvement of periodontitis.

 

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Track 12: Diabetes Advanced Technologies

NIDDK-funded researchers are developing a new tool, called an islet chip, to study islets—groups of cells in the pancreas. Islets contain several types of cells, including beta cells that make insulin. In people with type 1 diabetes, the body’s immune system attacks and destroys the beta cells. Researchers funded by the National Institute of Biomedical Imaging and Bioengineering(NIBIB) have developed a non-invasive device that can measure blood glucose levels without the standard finger prick. Researchers have also developed a flexible, wearable patch that can measure blood pressure and detect cardiovascular problems. This device could eventually help people living with diabetes, who are more likely to have high blood pressure and cardiovascular problems than people without diabetes.

 

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Track 13: Diabetes Research in Clinical Practice

The most recent of diabetes in clinical practice is on their main causes of blindness, kidney failure, heart attack, and stroke. The number of people affected by all types of diabetic disorders is now over four times complex than just 40 years ago. This has led the World Health Organization (WHO) to consider diabetes an epidemic, predicting it will soon be the seventh biggest cause of death worldwide. Development of a Microcell (Islet) Encapsulation Device to Cure Diabetes. Purpose: Islet transplantation is an encouraging approach to cure type 1 diabetes and some people with type 2 diabetes, but current treatment requires high dose toxic systemic immunotherapy to prevent rejection.

 

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Track 14: Stem Cell treatment in Diabetes

Stem cells treatments in Diabetes are being used for on-going research to help us explore the intricate ways in which our bodies process sugar and answer some important questions about the root causes of diabetes, such as:

• In type 1 of diabetes, why does the immune system begin to attack beta cells and no other cells in the pancreas or in other organs or tissues?
• In type 2 of diabetes, what causes the resistance to insulin?

Recently, there has been great progress in generation of beta cells from embryonic stem cells (ESCs) and induced pluripotent stem (IPS) cells. Laboratory studies help us better understand disease progression, what is the potential of genetic causes may be, and similarities and differences between patients. Researchers are using this information for diagnosing people earlier, to prevent disease progression, and more effectively treatments of diabetes.

 

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Track 15: Thyroid Disorders in Children, Teens and Adolescents

Thyroid disorders are common endocrine problem encountered in the paediatric and adolescent age group. Amongst the functional thyroid disorder’s hypothyroidism is far more common than hyperthyroidism.  Functional thyroid disorders lend themselves to effective treatment and monitoring strategies. The basic management principles remain similar to adults with thyroid dysfunction; experience in management of paediatric and adolescent thyroid disorders is particularly necessary to safeguard against long term detrimental effects of under-or overtreatment as it can have repercussion on the growth of the child. Prognosis in majority of the children tends to be good provided that timely and appropriate management is undertaken.

 

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Track 16:  Insulin Medication

Quite allot types of insulin are available. Each types has started to work at a different speed, known as “onset,” and its effects last a different length of time, known as “duration.” Most types of insulin reach a highest level, which is when they have the strongest effect. Then the effects of the insulin wear off over the next few hours. The technique you follow to take insulin may depend on your lifestyle, insurance plan, and preferences. Insulin is a hormone. It controls how much sugar is in our blood. A high level of sugar in our blood can cause problems in many parts of our body, including our heart, kidneys, eyes, and brain. Over time, this can lead to failure of our kidney.

 

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Track 17: Treatment and Diagnosis of Endocrine Diseases

There are a good range of treatment options for endocrine disorders. This is often because diseases of the system vary widely in both type and severity. The system is formed from different hormone -producing glands, and disorders arise when one or more of them either produces an excessive amount of or insufficient of a particular hormone. In some cases, the resulting hormone imbalance could also be mild enough to travel unnoticed or barely noticed and not require treatment. In other cases, like with hyperthyroidism, patients may exhibit unpleasant symptoms, including anxiety, rapid heartbeat, and fatigue. Medications may be used to alleviate these symptoms and prevent potentially serious complications over the long-term. Diagnosis of Endocrine Diseases involves Hormone testing, Genetic testing, Imaging studies and Urine tests etc.

Treatments for endocrine disorders generally fall into three categories:

• Medication:  If there is too much or too little of a certain hormone in the body, synthetic hormones may be administered to correct the imbalance and reduce symptoms. Chemotherapy may also be used to treat patients with cancer of an endocrine gland.
• Surgery:  In some cases, such as with cancerous and non-cancerous tumors on an endocrine gland, surgery and/or radiation therapy may be necessary. After the underlying problem has been resolved, hormone production should return to normal.
• Hormone Therapy: supplements to restore levels of certain hormones. This treatment may be right for you if you have abnormally low hormone levels. Hormone therapy also includes personalized insulin treatments for diabetes. Read more about medical and hormone replacement therapy for endocrine disorders.

 

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Track 18: Ketogenic Diet for Diabetes                                         

The keto diet (short for ketogenic diet) generally requires consuming 75% of your daily calories from fat, 20% from protein and just 5% from carbohydrates. Unlike some low-carb diets that recommend nixing sugar and processed grains (like white bread and pasta), going on the ketogenic diet also means eliminating nearly all carbs from your diet, including fruits, whole grains and some vegetables. Ketogenic diet proponents say that eating this way increases energy lowers diabetes risk and helps you lose weight quickly without any hunger. But the science behind ketogenic is very limited, with very few clinical studies in humans. Researchers have warned that there’s still a lot they don’t know about how high-fat, low-carb eating impacts for long-term health.

 

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Track 19: Natural therapy for Diabetes

The treatment of diabetes in Ayurveda calls for dietary changes that can help control blood glucose levels. The dietary recommendations suggested for the Ayurvedic treatment for diabetic patients include:

• The food consumed should be astringent or bitter. Bitter gourd, moong, barley is recommended to be included in the diet.
• The diet should include plenty of fruits and vegetables that have rich fibre content.
• Spices like turmeric, coriander, cumin and cardamon should be used while cooking.
• Instead of eating three heavy meals, 5 or 6 small meals can be eaten to prevent blood sugar level spikes.

 

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Track 20: COVID-19 Impacts People with Diabetes

Some people suffering from diabetes disease, that affects the body’s ability to produce or use the hormone insulin to reduce glucose (sugar) in the blood, may be concerned about being at higher risk of getting COVID -19. However, the exact cause of severe outcomes in patients with diabetes and COVID-19 is unknown, research over the years has recommended that people who have diabetes may have impaired immune systems, which would disturb their ability to heal from an illness or disease quickly. Moreover, if diabetes is especially uncontrolled for a long period of time, then they may cause inflammation, which also affects the immune system. Based on what the CDC is report at this time, people with type 1 or gestational diabetes might be at an increased risk for severe illness from Covid-19. Because COVID-19 is a new disease and we also don’t know as much as we’d like to about COVID-19 and how underlying medical conditions increase the risk for severe illness from COVID-19.

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In 2019 there have been 1.5 million deaths worldwide directly caused by the polygenic disorder. It had been the eighth leading reason behind death among each sex and therefore the fifth leading reason behind death in girls in 2019. Blood sugar levels that area unit higher than optimal, although below the diagnostic threshold for polygenic disorder, area unit a significant supply of mortality and morbidity. The diagnostic criterion for polygenic disorder is fast plasma Aldohexose 7.0 moll/L – a diagnostic purpose elect on the idea of microvascular complications like diabetic retinopathy. The danger of macro-vascular illness, like coronary failure or stroke, however, starts increasing well before this diagnostic purpose.

To perceive the complete impact of blood sugar levels on mortality so needs a glance at mortality associated with blood sugar as a risk issue. The entire burden of deaths from high blood glucose1 in 2019 has been calculable to quantity to 3.7 million. This variety includes 1.5 million polygenic disorder deaths, and a further a pair of 2 million deaths from vessel diseases, chronic aeropathy, and TB are associated with higher-than optimal blood sugar. Its magnitude highlights that top blood sugar causes an outsized burden of mortality on the far side of those deaths directly caused by the polygenic disorder. The biggest variety of deaths ensuing from high blood sugar occurs in upper-middle financial gain countries (1.5 million) and therefore the lowest variety in low-income countries (0.3 million). When the age of fifty, middle-income countries have the very best proportion of deaths attributed to high blood sugar, for each men and women. Except in high-income countries, the proportion of deaths because of high blood sugar for each men and girls’ area unit highest among the people 60–69 years. 43 percent of all deaths because of high blood sugar occur untimely, before the age of seventy years – Associate in nursing calculated to 1.6 million deaths worldwide.

Globally, high blood sugar causes concerning seven-membered deaths among men aged 20–69 and eight among girls aged 20– 69. The incidence and prevalence of the polygenic disorder have been increasing in countries throughout the globe. This case is clearly mirrored within the recently revealed information from the NCD-Risks (Non-Communicable Diseases Risk Factors Collaboration) study, showing that the number of people with polygenic disorder quadrupled between 1980 and 2014, notably in developing countries. European countries have not lost this upward trend. The polygenic disorder study according to Associate in Nursing age- and sex-adjusted total prevalence of 13.8%, and out of the affected people, 6% were unaware of their condition. moreover, the expectations for the longer term aren't reassuring: The International (diabetes polygenic disorder polygenic illness) Federation has calculated that this disease can have an effect on 642 million adults aged eighteen to seventy-nine years in 2040 (this same organization established the worth at 415 million in 2015), and about ninetieth of them can have polygenic disorder kind.

Market value on Diabetic Research:

The diabetes care drugs market reached USD 69.7 billion in 2019, and it is anticipated to register a CAGR of over 4.5% during the forecast period (2020-2025).

The significant growth in the market can be attributed to factors, such as the rising prevalence of diabetes and the increasing number of programs initiated by various health organizations related to health awareness. Currently, about 10% of all diabetes cases are Type-1 and the remaining are of Type-2.

As of 2019, North America accounted for a major share in the market, followed by Asia-Pacific. The increase in the number of diabetes patients is primarily due to increasing obesity among people caused by unhealthy diets and sedentary lifestyles. The market in Asia-Pacific is mainly driven by increasing demand for diabetes drugs from China and India. Currently, China has over 120 million diabetes patients, while the number of diabetes patients in India is expected to reach 87 million by 2025.